Holmes & Watson

Will Ferrell

As Sherlock Holmes

John C. Reilly

As Dr. John Watson

Rebecca Hall

As Dr. Grace Hart

Kelly Macdonald

As Mrs. Martha Hudson

Rob Brydon

As Inspector Lestrade

Lauren Lapkus

As Millie

Pam Ferris

As Queen Victoria

Ralph Fiennes

As Prof. James Moriarty / Jacob Musgrave

Adam Scherr

As Brawn

Kieran O'Brien

As PC Smalls

Noah Jupe

As Doxy

Bella Ramsey

As Flotsam

Colby Mulgrew

As Haybag

Scarlet Grace

As Pickle

Billy Jenkins

As Mud Fog

Michael Culkin

As The Judge

Jana Pérez

As Lestrade's Wife

Wolf Roth

As Sigmund Freud

Nathan Osgood

As Mark Twain

David Shackleton

As Albert Einstein

Paul Cassidy

As Charlie Chaplin

Ben Lee

As Houdini

Bronson Webb

As Jonathan Nightingale

Jamie-Rose Monk

As Mrs. Nightingale

Billy Zane

As Billy Zane

Jason Thorpe

As Butler

Robert Cawsey

As Waiter

Stanley Eldridge

As Waiter

Oliver Maltman

As Telegraph Operator

David Stoller

As Hudson's Guard

Jack Riley

As Newschild

Lilly Aspell

As Newschild

Ethan Rouse

As Newschild

Ellie Rose Eames

As Newschild

Jamie Baughan

As Titanic Ship Officer Liaison

Helen Duff

As Titanic Guest

Jess Liaudin

As Hangman

Wesley Kent-Hargreaves

As Weird Child Companion

Daniel Fearn

As Drooling Man Companion

Darren Lake

As Disorientated Man Companion

Martin Bishop

As Priest

Gerard Monaco

As Titanic Ship Officer

Michael Buffer

As Fight Fan #1

Bruce Buffer

As Fight Fan #2

Russell Wilcox

As Announcer

Hector Bateman-Harden

As Young Sherlock Holmes

Codie-Lei Eastick

As Young Watson

Laura Stevely

As Sherlock's Mother

Layla Rose Boyce

As Nicotine Stains / Nancy

Sadie Newman

As Jane

Harry Baxendale

As Seamus

Ella Bright

As Bridgette

Kenneth Hadley

As Headmaster

Paul Bigley

As Teacher #1

Sue Maund

As Teacher #2

Tommy Gene Surridge

As Inky Hands

Paddy Holland

As Tough Kid

Hugh Laurie

As Mycroft Holmes (uncredited)

Steve Coogan

As Gustav Klinger (uncredited)

Phil Hodges

As Mr. Algernon Barkworth (uncredited)

Sara Beasley

As Mrs. Frobisher (uncredited)

James Eeles

As Manager Mr. Petrucka (uncredited)

Paul T.T. Easter

As John (uncredited)

Jordan Long

As Herbert (uncredited)

Sonnyboy Skelton

As Doxy's Dad (uncredited)

Willem Dalby

As Newsie Man (uncredited)

Riley White

As Newsie Kid - Jimmy (uncredited)

Lochlan White

As Newsie Kid - Timmy (uncredited)

John Kinory

As Instructing Solicitor (uncredited)

Benjamin Lok

As Courtroom Person 3 (uncredited)

Joseph Macnab

As Fitness Instructor (uncredited)

Martin Bassindale

As One Man Band (uncredited)

Amelia O'Loughlin

As White Star-Line Girl (uncredited)

Matthew Di Liello

As Telly-Phone Assistant (uncredited)

Craig Thomas Lambert

As Yeoman of the Guard (uncredited)

Jorge Leon

As British Soldier (uncredited)

Martyn Mayger

As Buckingham Palace Guest (uncredited)

Hugh O'Brien

As Garden Party Guest (uncredited)

Deepak Anand

As Nobleman (uncredited)

Shawn Dixon

As Upper Class Gentleman #1 (uncredited)

Anthony Richard Rowe

As Victorian Gentleman (uncredited)

Mick Slaney

As Docker (uncredited)

Karl Farrer

As Russian Merchant (uncredited)