On the Edge

John Goodman

As The Dean (segment "Happy Birthday")

Sydney Tamiia Poitier

As Hannah (segment "Happy Birthday")

Beverly D'Angelo

As Bag Lady (segment "Happy Birthday")

Christopher Lloyd

As Attorney Bum (segment "Happy Birthday")

David Hyde Pierce

As Barney (segment "Happy Birthday")

Caroline Rhea

As Monica (segment "Happy Birthday")

Jenica Bergere

As Sally (segment "Happy Birthday")

Ken Hudson Campbell

As Security Guard (segment "Happy Birthday")

Roman Danylo

As Donald (segment "Happy Birthday")

Kimiko Gelman

As May Lee Ha (segment "Happy Birthday")

Jean Kasem

As Nurse (segment "Happy Birthday")

Taylor Negron

As Policeman (segment "Happy Birthday")

Travis Wester

As Chute Boy (segment "Happy Birthday")

Dondré Whitfield

As Man in Elevator (segment "Happy Birthday")

Marissa Jaret Winokur

As Dean's Secretary (segment "Happy Birthday")

Bruce Davison

As (segment "The Other Side")

Anthony LaPaglia

As Dr. Maas (segment "The Other Side")

Karen Sillas

As Anna (segment "The Other Side")

Andie MacDowell

As Lisa (segment "Reaching Normal")

Paul Rudd

As Kenneth (segment "Reaching Normal")

Joey Lauren Adams

As Sarah (segment "Reaching Normal")

Alan Rosenberg

As Frank (segment "Reaching Normal")

Joel Grey

As Dr. Mensley (segment "Reaching Normal")

Jolene Blalock

As Charlie's Wife (wraparound segments)

Scott Lowell

As Charlie (wraparound segments)

Stephen Tobolowsky

As Tom (wraparound segments)

Kathleen Wilhoite

As Lucy (wraparound segments)

Ellen DeGeneres

As Operator (segment "Reaching Normal") (uncredited)

Helen Mirren

As Distinguished Woman (segment "Happy Birthday") (uncredited)