Tammy

Melissa McCarthy

As Tammy

Susan Sarandon

As Pearl

Kathy Bates

As Lenore

Mark Duplass

As Bobby

Gary Cole

As Earl

Allison Janney

As Deb

Dan Aykroyd

As Don

Sandra Oh

As Susanne

Nat Faxon

As Greg

Toni Collette

As Missi

Ben Falcone

As Keith Morgan

Sarah Baker

As Becky

Rich Williams

As Larry

Steve Little

As Jet Ski Rental Guy

Dakota Lee

As Kathleen

Mark L. Young

As Jesse

Mia Rose Frampton

As Karen

Steve Mallory

As Cashier

Big Al Hall

As Possum Creek Bluegrass Band

Jones Smith

As Possum Creek Bluegrass Band

Joe Baxter

As Possum Creek Bluegrass Band

Benjamin Chontos

As Possum Creek Bluegrass Band

Sean Gould

As Possum Creek Bluegrass Band

Keith Welborn

As DJ

Oscar Gale

As Javier

Justin Smith

As Paramedic

Willie Hill

As Prison Guard

Zach Hanner

As Man at Blue Post Bar-B-Que

Jason Vail

As Man at Blue Post Bar-B-Que

Leon Lamar

As Old Man with Walker

Larry Dorf

As Officer Mannis

Ricky Muse

As Officer Curtis

Barbara Weetman

As Officer Carty

William Flaman

As La Grange Bail Cop

Rey Hernandez

As Cop at Lakehouse

Penn Holderness

As News Anchor

Michelle Li

As News Reporter

Raven Angeline Whisnant

As Charlotte

Damon Jones

As Jerry Miller

Sandy McCarthy

As Old Lady Leaving a Bar

Margo Passas

As Old Lady Leaving a Bar

Sheila Brothers

As Connie (uncredited)

Rob Springer

As Gene the Cook (uncredited)

Cricket Ellis

As Lunchroom Lady (uncredited)

Kaitlyn Christian

As Canoe Teen (uncredited)

J.R. Rodriguez

As Kentucky Trooper (uncredited)

Michelle Rivera Huckaby

As Arresting Cop (uncredited)

David Andrew Nash

As Morningside Guard (uncredited)