Pootie Tang

Lance Crouther

As Pootie Tang

JB Smoove

As Trucky

Jennifer Coolidge

As Ireenie

Reg E. Cathey

As Dirty Dee

Robert Vaughn

As Dick Lecter

Wanda Sykes

As Biggie Shorty

Chris Rock

As JB / Radio DJ / Pootie's Father

Mario Joyner

As Lacey

Cathy Trien

As Stacy

Dave Attell

As Frank

Laura Kightlinger

As Anchor Woman

Christopher Wynkoop

As Sheriff

Rick Shapiro

As Shakey

Qiana Drew

As Singing Lady

Lorria Richards

As Singing Lady

J.D. Williams

As Froggy

Tara Jeffers

As Solo Girl Singer

Cole Hawkins

As Little Pootie

Andy Richter

As Record Executive

Kristen Bell

As Record Executive's Daughter

Ray Wills

As Board Director

Robert Trumbull

As Board Director

Jim Earl

As Eddie

David Cross

As Dennis

Chuck Jeffreys

As Bad Bitty

Tammy Faye Starlite

As Dirty Dee Girl

Jodi Michelle Pynn

As Dirty Dee Girl

Stacy Renae

As Sidewalk Girl

Alem Brhan Sapp

As Guitar Player

Joseph Dolphin

As Greasy

Todd Barry

As Greasy

Keesha Sharp

As Party Girl

Greg Hahn

As Prison Guard

Jon Glaser

As Recording Engineer (as John Glaser)

William Stephenson

As Fast Food Cook

Robin Montague

As Screaming Woman

Devon Malik Beckford

As Sweet Little Boy

Missy Elliott

As Diva

Bryan Hearne

As Little Trucky

Ebony Jo-Ann

As Pootie's Mother

Bob Costas

As Bob Costas

Conan O'Brien

As Conan O’Brien (uncredited)

Brian Donahue

As Pootie Impostor (uncredited)

Michelle Robinson

As Jilted Woman

Keenan Shimizu

As Big Father

Linda Murrell

As Burger Joint Reporter

Michael Broughton

As Bad Bitty Goon

Tony Rhune

As Bad Bitty Goon

Andy Duppin

As Dirty Dee Goon

David S. Lomax

As Dirty Dee Goon

Bob Colletti

As Gorilla

Lanette Ware

As Flashback Woman (uncredited)

Brian Smyj

As Pootie Impersonator (uncredited)

Diandra Newlin

As Pork Chunks Girl (uncredited)

Cecelia Antoinette

As Party Girl (uncredited)